MedSafe Medication Disposal System

Comprehensive medication collection kiosk and disposal solution

MedSafe is an unused and expired medication disposal system. This easy-to-operate system accepts controlled (Schedules II-V), non-controlled, and over-the-counter medicines.

MedSafe meets the requirements of the DEA Controlled Substances Act.

Request more information or call us at (800) 772-5657.

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MedSafe® Collection Receptacles placed in communities for proper drug disposal

MedSafe® medication disposal Inner Liners returned for proper destruction

Pounds of medications safely collected and properly destroyed with MedSafe®

Pounds removed from communities since 2009 with MedSafe® and TakeAway


+as of 01/08/2020

About MedSafe

MedSafe combines a stainless-steel collection receptacle with a removable prepaid shipback inner liner. When the inner liner fills, authorized persons can safely remove the liner from the collection receptacle, seal it, and return it via common carrier. Inner lines are treated by incineration, rendering the pharmaceuticals non-retrievable per the DEA's destruction standard.

MedSafe medication disposal in a retail pharmacy


MedSafe is designed for long-term care facilities (LTCF), licensed law enforcement, and narcotic treatment centers, as well as retail pharmacies and hospitals and clinics with on-site pharmacies.


MedSafe Benefits

  • Cost-effective and easy-to-manage system that meets DEA regulations
  • Comingled collection of controlled and non-controlled pharmaceuticals
  • Inner liners transferred by a common carrier
  • Controlled drugs destroyed using incineration, meeting the DEA's destruction standard of non-retrievability

MedSafe Features

  • 14-gauge powder-coated steel collection receptacle
  • 4-times stronger collection receptacle than competitors with 18-gauge steel receptacles
  • One-way medicine drop with locking door
  • Double-locked front door access
  • Secures to a permanent structure
  • Serialized liners with prepaid common carrier return

 Download MedSafe Brochure

MedSafe Specifications

38-Gallon MedSafe

38-Gallon MedSafe is ideal for facilities, such as retail pharmacies, that generate larger amounts of pharmaceutical waste from ultimate users. MedSafe increases foot traffic for retail pharmacies by providing a much-needed service to the community.

MedSafe Medication Disposal Collection Receptacle - 38-Gallon

MedSafe 38-Gallon Collection Receptacle Specifications

  • Overall Dimensions: 43.75" x 22.5" x 21.25"
  • Top Opening Dimensions: 5.5" x 13"

38-Gallon Inner Liner Specifications

  • Constructed of two 200# Test Corrugated Fiberboard Enclosures
  • Outer Box Dimensions: 18.25" x 18.25" x 27"
  • Inner Box Dimensions: 17.75" x 17.75" x 26.375"
  • Two 4-Mil Polyethylene Plastic Bags
  • Eighteen 4" x 6" Absorbent Pads
MedSafe Medication Disposal Collection Receptacle - 38-Gallon

 Download MedSafe 38 Spec Sheet

18-Gallon MedSafe

18-Gallon MedSafe is perfect for facilities that generate smaller amounts of pharmaceutical waste, such as long-term care facilities. MedSafe is convenient and easy to use. Nurses no longer have to spend time mixing unused medication with kitty litter or popping pills out of bingo cards.

MedSafe Medication Disposal Collection Receptacle - 18-Gallon

MedSafe 18-Gallon Collection Receptacle Specifications

  • Overall Dimensions: 38.25" x 17" x 16.25"
  • Top Opening Dimensions: 5.5" x 13"

18-Gallon Inner Liner Specifications

  • Constructed of two 200# Test Corrugated Fiberboard Enclosures
  • Outer Box Size: 13.5" x 13.5" x 22.5"
  • Inner Box Size: 13" x 13" x 22"
  • Two 4-Mil Polyethylene Plastic Bags
  • Ten 4" x 6" Absorbent Pads
MedSafe Medication Disposal Collection Receptacle - 38-Gallon

 Download MedSafe 18 Spec Sheet

Hundreds of Organizations Are Helping Their Communities Dispose of Unused Medications with MedSafe®

Department of Veterans Affairs

Department of Defense

State Boards of Pharmacy

Behavioral Health and Recovery Services

Nonprofit Coalitions

State Health & Human Services

Major Pharmacy Chains

Independent Pharmacies

Healthcare Systems

MedSafe Headlines

Northwest Florida Daily News

"By law, the pharmacy could not legally accept dispensed prescriptions. That changed last fall," said Maj. Marcio Fletes, director of outpatient pharmacy operations here. "The MEDSAFE unit definitely meets our patients' needs."

Ilka Cole, Northwest Florida Daily News
Army Flier

In an effort to improve safety among the Fort Rucker community, Lyster Army Health Clinic added a new option for medication disposal for its beneficiaries.

Located in the pharmacy lobby, the new MedSafe drop box allows patients to safely dispose of any unwanted or expired medications.

Jenny Stripling, Army Flier
Deseret News

That is until now. At nearly two dozen of its community pharmacies across the state, Intermountain Healthcare has installed secure drop-off boxes called "MedSafe." Utah is one of a few states in the nation installing these. People who have unused medications can deposit them in the boxes for proper disposal.

Keith McCord, Deseret News


Medsafe Boxes are placed at Northside Pharmacy and the Medicine Bin in Lafayette. The safe disposal boxes allow customers to drop off unwanted or expired medications with the convenience of picking up their current medications at the pharmacy.

"I'm so proud that we have something situated in the community now that's 24/7. You don't have to wait until October, or until April, or whenever. Cause it's twice a year. You don't have to hold onto medication because you can walk directly into your pharmacy and drop that medication off" Mechelle Richard

Munson Healthcare is installing MedSafe medication disposal containers at its hospitals.

"Use of medication disposal containers could help prevent opioid misuse, overdose and addiction." James Whelan, M.D.

Liberal Area Coalition for Families Director Sarah Foreman and Liberal Police Department Evidence Supervisor Allison Clark are joined by Police Chief Dennis Mulanax and Chamber Ambassadors in cutting the ribbon on the new MedSafe drug disposal box at the police department Tuesday afternoon. The High Plains Daily Leader

"I think the goal of any MedSafe disposal is to get either prescribed drugs off the streets, out of the wrong hands, and expired medication also not in the water system, not on the streets, not in dumpsters, but safely disposed of and then incinerated" Sarah Foreman

The hospital vetted several medication disposal companies according to price, ease of use and the manner in which they destroyed medication, and ultimately chose the MedSafe system from Sharps Compliance Inc. The pharmacy department worked to modify their Drug Enforcement Administration license in order to become an authorized medication collector.

"The utilization of the medication collection bin has been much greater than initially anticipated." Lisa Block, PharmD

One of the many topics that came about at the event was the lack of opportunity to dispose of unused medication to prevent from potential abuse, which triggered a response plan from H.O.P.E and members of the community.

"We have a new resource that will help us decrease the risk of accidental overdose or the development of addictions." Savannah Jacquay

Carlson Drug, 821 Sixth Street, is adding a secure metal dropbox where people can get rid of unused or expired medications. The Umatilla Police Department procured the dropbox with grant funding from Good Shepherd Community Health Foundation.

"People are always asking her how they can safely dispose of the rest of their prescription once they no longer need the drugs they were taking." Cathy Putnam, owner of Carlson Drug

In an effort to improve safety in Iron County related to medication disposal, Aspirus Iron River Hospital & Clinics has provided a grant for two drug disposal receptacles in the community.

"It's important to properly dispose of unused medications to reduce the risk of accidental exposure or intentional misuse." Aspirus Iron River Hospital Pharmacist, Phil Wojdula

Excess prescription and over-the-counter drugs can pose a serious risk in your home. Naval Branch Health Clinic (NBHC) Groton is helping the Naval Submarine Base New London (SUBASE) community fight back against the dangers of unneeded, unused and expired drugs by offering Drug Take Back at NBHC's Pharmacy.

"Proper drug disposal lowers the risk of abuse, accidental ingestion or environmental contamination." Pharmacist Lt. Cmdr. Michael Terrenzi

MedSafe Frequently Asked Questions

Who can purchase a MedSafe?

MedSafe is designed for long-term care facilities (LTCF), licensed law enforcement, and narcotic treatment centers, as well as retail pharmacies and hospitals and clinics with on-site pharmacies. When used in long-term care, an approved "collector" must manage the MedSafe collection receptacle program.


Who is a "collector"?

A collector is an approved DEA registrant that applies with the DEA to collect controlled substances from ultimate users. Retail pharmacies can install and manage a MedSafe collection receptacle program by registering with the DEA as a collector. Additionally, retail pharmacies may install and manage MedSafe programs at LTCFs.


Can I comingle non-controlled medications and controlled substances in MedSafe?

Yes. Both controlled (Schedules II-V) and non-controlled substances can be disposed of in the MedSafe collection receptacle. With MedSafe, facilities have one complete solution for disposal of non-hazardous unused medications.

How much does the MedSafe cost?

The MedSafe medication collection and disposal systems is available for sale or lease to facilities approved by the DEA to manage collection receptacle programs. For more information on each option and pricing, please contact a Sharps Compliance sales consultant at (800) 772-5657.


How do I order a new inner liner?

Inner liners are available for purchase in a four-pack option or they are auto-shipped when the MedSafe system is leased. Pricing is dependent on program purchase/lease options. To learn more about MedSafe and which option best meets your facility's needs, please contact a Sharps Compliance sales consultant at (800) 772-5657.


Where can I find information on the DEA regulations?

A link to the full regulations is here. You can access links for DEA registrants, LTCFs and more here.


Is marketing support available?

Sharps Compliance has created materials to help you market MedSafe to your community. You will have access to postcards, flyers, posters, and much more so you can spread the word about MedSafe.

Sharps Compliance, Inc. (Sharps) fully complies with DOT regulations for the transport of such drugs collected for disposal as authorized by the DOT under Special Permit # DOT-SP 20284. Click the link for the Special Permit under which the Company operates.

MedSafe is a patent-pending solution from Sharps Compliance.